Healthcare

This study examined how behavioral, emotional, and contextual factors influence Filipino students' willingness to use artificial intelligence (AI) for mental health support. Results showed that habit had the strongest effect on willingness, followed by comfort, emotional benefit, facilitating conditions, and perceived usefulness. Students who used AI tools regularly felt more confident and open to relying on them for emotional support. Empathy, privacy, and accessibility also increased comfort a

Using a stylised coordination problem drawn from inpatient capacity management, three archetypal forms of AI deployment are described: effort-reducing technologies, observability-oriented systems, and interventions that alter underlying incentive structures. Effort reduction and observability may improve performance within existing patterns of behaviour but do not, in general, change which actions are individually rational. As a result, such interventions are typically absorbed into existing equ

3D human pose estimation is a key enabling technology for applications such as healthcare monitoring, human-robot collaboration, and immersive gaming, but real-world deployment remains challenged by viewpoint variations. Existing methods struggle to generalize to unseen camera viewpoints, require large amounts of training data, and suffer from high inference latency. We propose MoViD, a viewpoint-invariant 3D human pose estimation framework that disentangles viewpoint information from motion fea

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling of such medical datasets are highly challenging due to the reliance on clinical expertise and strict ethical and privacy constraints, resulting in a scarcity of large-scale unified medical datasets and hindering the development of powerful medical foundation mo

In the field of Large Language Models (LLMs), Attention Residuals have recently demonstrated that learned, selective aggregation over all preceding layer outputs can outperform fixed residual connections. We propose Cross-Stage Attention Residuals (XAttnRes), a mechanism that maintains a global feature history pool accumulating both encoder and decoder stage outputs. Through lightweight pseudo-query attention, each stage selectively aggregates from all preceding representations. To bridge the ga

Embodied Artificial Intelligence (Embodied AI) integrates perception, cognition, planning, and interaction into agents that operate in open-world, safety-critical environments. As these systems gain autonomy and enter domains such as transportation, healthcare, and industrial or assistive robotics, ensuring their safety becomes both technically challenging and socially indispensable. Unlike digital AI systems, embodied agents must act under uncertain sensing, incomplete knowledge, and dynamic hu

Large Vision-Language Models (LVLMs) have achieved impressive performance across multimodal understanding and reasoning tasks, yet their internal safety mechanisms remain opaque and poorly controlled. In this work, we present a comprehensive framework for diagnosing and repairing unsafe channels within LVLMs (CARE). We first perform causal mediation analysis to identify neurons and layers that are causally responsible for unsafe behaviors. Based on these findings, we introduce a dual-modal safet

We study cross-modal alignment between independently pretrained vision (DINOv2) and language (all-MiniLM-L6-v2) encoders using the functional map framework from computational geometry, which represents correspondence between representation manifolds as a compact linear operator between graph Laplacian eigenbases. While the framework underperforms Procrustes alignment and relative representations for cross-modal retrieval across all supervision budgets, it reveals a structural property of multimo

The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has ignited a data-centric AI paradigm that emphasizes better data characterization, quality, and scale. In healthcare AI, obtaining and processing high-quality clinical data records has been a longstanding challenge, encompassing data quantity, annotation, patient pr

Predictive modeling on sequential event data is critical for fraud detection and healthcare monitoring. Existing data-driven approaches learn correlations from historical data but fail to incorporate domain-specific sequential constraints and logical rules governing event relationships, limiting accuracy and regulatory compliance. For example, healthcare procedures must follow specific sequences, and financial transactions must adhere to compliance rules. We present a neuro-symbolic approach int

Electrocardiograms (ECGs) are among the most widely available clinical signals and play a central role in cardiovascular diagnosis. While recent foundation models (FMs) have shown promise for learning transferable ECG representations, most existing pretraining approaches treat leads as independent channels and fail to explicitly leverage their strong structural redundancy. We introduce the latent attention masked autoencoder (LAMAE) FM that directly exploits this structure by learning cross-lead

Uncertainty quantification is essential for deploying machine learning models in high-stakes domains such as scientific discovery and healthcare. Conformal Prediction (CP) provides finite-sample coverage guarantees under exchangeability, an assumption often violated in practice due to distribution shift. Under covariate shift, restoring validity requires importance weighting, yet accurate density-ratio estimation becomes unstable when training and test distributions exhibit limited support overl

Despite recent advances in medical vision-language pretraining, existing models still struggle to capture the diagnostic workflow: radiographs are typically treated as context-agnostic images, while radiologists' gaze -- a crucial cue for visual reasoning -- remains largely underexplored by existing methods. These limitations hinder the modeling of disease-specific patterns and weaken cross-modal alignment. To bridge this gap, we introduce CoGaze, a Context- and Gaze-guided vision-language pretr

Human age estimation from facial images represents a challenging computer vision task with significant applications in biometrics, healthcare, and human-computer interaction. While traditional deep learning approaches require extensive labeled datasets and domain-specific training, recent advances in large vision-language models (LVLMs) offer the potential for zero-shot age estimation. This study presents a comprehensive zero-shot evaluation of state-of-the-art Large Vision-Language Models (LVLM

While powerful in image-conditioned generation, multimodal large language models (MLLMs) can display uneven performance across demographic groups, highlighting fairness risks. In safety-critical clinical settings, such disparities risk producing unequal diagnostic narratives and eroding trust in AI-assisted decision-making. While fairness has been studied extensively in vision-only and language-only models, its impact on MLLMs remains largely underexplored. To address these biases, we introduce

Background: More than 80% of U.S. cancer care is delivered in community settings, where survival remains worse than at academic centers. Clinicians must integrate genomics, staging, radiology, pathology, and changing guidelines, creating cognitive burden. We evaluated OncoBrain, an AI clinical reasoning platform for oncology treatment-plan generation, as an early step toward OGI. Methods: OncoBrain combines general-purpose LLMs with a cancer-specific graph retrieval-augmented generation layer, a

Speech Emotion Recognition (SER) systems have growing applications in sensitive domains such as mental health and education, where biased predictions can cause harm. Traditional fairness metrics, such as Equalised Odds and Demographic Parity, often overlook the joint dependency between demographic attributes and model predictions. We propose a fairness modelling approach for SER that explicitly captures allocative bias by learning the joint relationship between demographic attributes and model e

The widespread adoption of CT has notably increased the number of detected lung nodules. However, current deep learning methods for classifying benign and malignant nodules often fail to comprehensively integrate global and local features, and most of them have not been validated through clinical trials. To address this, we developed DeepFAN, a transformer-based model trained on over 10K pathology-confirmed nodules and further conducted a multi-reader, multi-case clinical trial to evaluate its e

We present a unified system addressing both Subtask 3 (answer generation) and Subtask 4 (evidence sentence alignment) of the ArchEHR-QA Shared Task. For Subtask 3, we apply two-stage Quantised Low-Rank Adaptation (QLoRA) to Qwen3-4B loaded in 4-bit NF4 quantisation: first on 30,000 samples from the emrQA-MedSQuAD corpus to establish clinical domain competence, then on the 20 annotated development cases to learn the task-specific output style. Our system achieves an overall score of 32.87 on the

Alzheimer's disease (AD) is a growing global health challenge as populations age, and timely, accurate diagnosis is essential to reduce individual and societal burden. However, real-world AD assessment is hampered by incomplete, heterogeneous multimodal data and variability across sites and patient demographics. Although large language models (LLMs) have shown promise in biomedicine, their use in AD has largely been confined to answering narrow, disease-specific questions rather than generating

We present a Sovereign AI architecture for clinical triage in which all inference is performed on-device and inbound data is delivered via a physically unidirectional channel, implemented using receive-only broadcast infrastructure or certified hardware data diodes, with no return path to any external network. This design removes the network-mediated attack surface by construction, rather than attempting to secure it through software controls. The system performs conversational symptom intake, i

Recent advances in multimodal large language models enable new possibilities for image-based decision support. However, their reliability and operational trade-offs in neuroimaging remain insufficiently understood. We present a comprehensive benchmarking study of vision-enabled large language models for 2D neuroimaging using curated MRI and CT datasets covering multiple sclerosis, stroke, brain tumors, other abnormalities, and normal controls. Models are required to generate multiple outputs sim

Clinical documentation is a critical factor for patient safety, diagnosis, and continuity of care. The administrative burden of EHRs is a significant factor in physician burnout. This is a critical issue for low-resource languages, including Finnish. This study aims to investigate the effectiveness of a domain-aligned natural language processing (NLP); large language model for medical transcription in Finnish by fine-tuning LLaMA 3.1-8B on a small validated corpus of simulated clinical conversat

Online Health Communities connect patients for peer support, but users face a discovery challenge when they have minimal prior interactions to guide personalization. We study recommendation under extreme interaction sparsity in a survey driven setting where each user provides a 16 dimensional intake vector and each support group has a structured feature profile. We extend Neural Collaborative Filtering architectures, including Matrix Factorization, Multi Layer Perceptron, and NeuMF, with an auxi

Purpose: To design, implement, evaluate, and report on the regulatory requirements of a self-hosted LLM infrastructure for radiology adhering to the principle of least privilege, emphasizing technical feasibility, network isolation, and clinical utility. Materials and Methods: The isolation-first, containerized LLM inference stack relies on strict network segmentation, host-enforced egress filtering, and active isolation monitoring preventing unauthorized external connectivity. An accompanying d

We introduce WhaVax, a new expert-annotated dataset of vaccine-related WhatsApp messages collected from large Brazilian public groups spanning multiple pandemic years. The dataset was constructed through a rigorous, carefully designed pipeline that integrates keyword-based data collection, semantic deduplication to remove near-duplicate content, and a multi-stage annotation protocol conducted by medical specialists. This process produced a high-quality gold-standard corpus, characterized by subs

Medical conversations offer insights into clinical communication often absent from Electronic Health Records. However, developing reliable clinical Natural Language Processing (NLP) models is hampered by the scarcity of domain-specific datasets, as clinical data are typically inaccessible due to privacy and ethical constraints. To address these challenges, we present a pipeline for generating synthetic Dutch medical dialogues using a Dutch fine-tuned Large Language Model, with real medical conve

Code agents resolve 65-70% of SWE-bench Verified issues, but Pass@1 cannot tell us why the rest fail, and, as we show, capable-model failures are systematically misdiagnosed without trajectory data. We introduce TRAJEVAL, a training-free decomposition of agent trajectories into reference-patch-aligned search, read, and edit stages, and apply it across 16,758 trajectories spanning three architectures and seven models. The dominant failure of capable models is not localization: 60-69% of failures

Ethical discourse on AI in healthcare has focused predominantly on back-end concerns such as bias, fairness and explainability, while the front-end interface, where patients and clinicians actually encounter AI outputs, remains under explored. This paper identifies imbalanced user-AI relationships as a distinct class of front-end ethical failure: patients are rendered highly visible to AI systems through data inference, yet cannot understand, question or influence how they are represented. Throu

Currently, a central challenge and bottleneck in the deployment and validation of computer-aided diagnosis (CAD) models within the field of medical imaging is data scarcity. For lung cancer, one of the most prevalent types worldwide, limited datasets can delay diagnosis and have an impact on patient outcome. Generative AI offers a promising solution for this issue, but dealing with the complex distribution of full Hounsfield Unit (HU) range lung CT scans is challenging and remains as a highly co

Biohacking, the self-directed application of biotechnology, digital tools, and lifestyle interventions, has rapidly converged with gut microbiome science to create adaptive, individualized, and minimally invasive precision-health paradigms. This narrative review integrates current evidence on diet-based modulation, microbial therapeutics (probiotics, prebiotics, postbiotics, and fecal microbiota transplantation), and synthetic-biology approaches (engineered strains and phage or synthetic consort

Adapters are often selected and deployed based on nominal labels (e.g., instruction-tuned), which implicitly suggest what capability improves after adaptation. We test whether nominal training objectives reliably align with realized cross-task capability gains by evaluating the same LoRA adapter across tasks. Our strongest evidence is tied to strict, automatically verifiable instruction following as measured by IFEval: across multiple seeds, base models, and LoRA settings, nominal labels recurre

Unsupervised Domain Adaptation (UDA) is essential for deploying medical segmentation models across diverse clinical environments. Existing methods are fundamentally limited, suffering from semantically unaware feature alignment that results in poor distributional fidelity and from pseudo-label validation that disregards global anatomical constraints, thus failing to prevent the formation of globally implausible structures. To address these issues, we propose SHAPE (Structure-aware Hierarchical U

Deformable image registration plays a fundamental role in medical image analysis by enabling spatial alignment of anatomical structures across subjects. While recent deep learning-based approaches have significantly improved computational efficiency, many existing methods remain limited in capturing long-range anatomical correspondence and maintaining deformation consistency. In this work, we present a cycle inverse-consistent transformer-based framework for deformable brain MRI registration. Th

Multimodal AI systems have achieved remarkable performance across a broad range of real-world tasks, yet the mechanisms underlying visual-language reasoning remain surprisingly poorly understood. We report three findings that challenge prevailing assumptions about how these systems process and integrate visual information. First, Frontier models readily generate detailed image descriptions and elaborate reasoning traces, including pathology-biased clinical findings, for images never provided; we

Protecting patient privacy remains a fundamental barrier to scaling machine learning across healthcare institutions, where centralizing sensitive data is often infeasible due to ethical, legal, and regulatory constraints. Federated learning offers a promising alternative by enabling privacy-preserving, multi-institutional training without sharing raw patient data; however, real-world deployments face severe challenges from data heterogeneity, site-specific biases, and class imbalance, which degr

Compliance monitoring in rule-governed domains (tax administration, clinical protocol adherence, environmental regulation) faces three structural obstacles that standard machine learning does not simultaneously address: the absence of labeled outcomes at deployment, strategically missing observations where non-compliant entities selectively withhold evidence, and a regulatory environment that changes faster than any supervised model can be retrained. We introduce Rule-State Inference (RSI), a Ba

Modern clinical practice increasingly depends on reasoning over heterogeneous, evolving, and incomplete patient data. Although recent advances in multimodal foundation models have improved performance on various clinical tasks, most existing models remain static, opaque, and poorly aligned with real-world clinical workflows. We present Cerebra, an interactive multi-agent AI team that coordinates specialized agents for EHR, clinical notes, and medical imaging analysis. These outputs are synthesiz

Sepsis, life-threatening acute organ dysfunction due to infection [ 1 ], is a global health priority [ 2 , 3 ] with approximately 49 million cases and 13 million sepsis-related deaths each year [ 4 , 5 , 6 ]. Beyond being acutely deadly, sepsis contributes to new and worsened physical, cognitive, and mental health problems in many survivors [ 7 , 8 ]. Early identification and treatment are critical to improving outcomes.

When organisations adopt commercial AI systems for decision support, they inherit value judgements embedded by vendors that are neither transparent nor renegotiable. The governance puzzle is not whether AI can support decisions but which recommendations the system can actually produce given how its vendor has configured it. I formalise this as a behavioural feasible set, the range of recommendations reachable under vendor-imposed alignment constraints, and characterise diagnostic thresholds for