Research (36)
Artificial intelligence in public health: promises, challenges, and an agenda for policy makers and public health institutions
Artificial intelligence (AI) can rapidly analyse large and complex datasets, extract tailored recommendations, support decision making, and improve the efficiency of many tasks that involve the processing of data, text, or images. As such, AI has the potential to revolutionise public health practice and research, but accompanying challenges need to be addressed. AI can be used to support public health surveillance, epidemiological research, communication, the allocation of resources, and other f
Shaping the Future of Healthcare: Ethical Clinical Challenges and Pathways to Trustworthy AI
Background/Objectives: Artificial intelligence (AI) is transforming healthcare, enabling advances in diagnostics, treatment optimization, and patient care. Yet, its integration raises ethical, regulatory, and societal challenges. Key concerns include data privacy risks, algorithmic bias, and regulatory gaps that struggle to keep pace with AI advancements. This study aims to synthesize a multidisciplinary framework for trustworthy AI in healthcare, focusing on transparency, accountability, fairne
Artificial intelligence for modeling and understanding extreme weather and climate events
In recent years, artificial intelligence (AI) has deeply impacted various fields, including Earth system sciences, by improving weather forecasting, model emulation, parameter estimation, and the prediction of extreme events. The latter comes with specific challenges, such as developing accurate predictors from noisy, heterogeneous, small sample sizes and data with limited annotations. This paper reviews how AI is being used to analyze extreme climate events (like floods, droughts, wildfires, an
Generative Artificial Intelligence: Evolving Technology, Growing Societal Impact, and Opportunities for Information Systems Research
Abstract The continuing, explosive developments in generative artificial intelligence (GenAI), built on large language models and related algorithms, has led to much excitement and speculation about the potential impact of this new technology. Claims include artificial intelligence (AI) being poised to revolutionize business and society and dramatically change personal life. However, it is not clear how this technology, with its significantly distinct features from past AI technologies, has tran
Exploring the Ethical Challenges of Conversational AI in Mental Health Care: Scoping Review
BACKGROUND: Conversational artificial intelligence (CAI) is emerging as a promising digital technology for mental health care. CAI apps, such as psychotherapeutic chatbots, are available in app stores, but their use raises ethical concerns. OBJECTIVE: We aimed to provide a comprehensive overview of ethical considerations surrounding CAI as a therapist for individuals with mental health issues. METHODS: We conducted a systematic search across PubMed, Embase, APA PsycINFO, Web of Science, Scopus,
Investigating the higher education institutions’ guidelines and policies regarding the use of generative AI in teaching, learning, research, and administration
Abstract This study examined the guidelines issued by the top 50 U.S. universities regarding the use of Generative AI (GenAI) in academic and administrative activities. Employing a mixed methods approach, the research combined topic modeling, sentiment analysis, and qualitative thematic analysis to provide a comprehensive understanding of institutional responses to GenAI. Topic modeling identified four core topics: Integration of GenAI in Learning and Assessment, GenAI in Visual and Multimodal M
From Neural Networks to Emotional Networks: A Systematic Review of EEG-Based Emotion Recognition in Cognitive Neuroscience and Real-World Applications
BACKGROUND/OBJECTIVES: This systematic review presents how neural and emotional networks are integrated into EEG-based emotion recognition, bridging the gap between cognitive neuroscience and practical applications. METHODS: Following PRISMA, 64 studies were reviewed that outlined the latest feature extraction and classification developments using deep learning models such as CNNs and RNNs. RESULTS: Indeed, the findings showed that the multimodal approaches were practical, especially the combina
Artificial intelligence for modelling infectious disease epidemics
Unveiling the barriers to digital transformation in higher education institutions: a systematic literature review
This study investigates the challenges hindering the implementation of Digital Transformation (DT) in Higher Education Institutions (HEIs) by thoroughly reviewing the literature. It identifies multiple dimensions and subdimensions of these barriers to offer valuable insights to help HEIs navigate their transformation processes successfully. By doing so, they can effectively address the changing requirements of students, faculty, administration, and other stakeholders in an increasingly digital e
Impact of Information and Communication Technologies on Democratic Processes and Citizen Participation
Background: This systematic review will address the influence of Information and Communication Technologies (ICTs) on democratic processes and citizens’ participation, which is enabled by such tools as social media, e-voting systems, e-government initiatives, and e-participation platforms. Methods: Based on an in-depth analysis of 46 peer-reviewed articles published between 1999 and 2024, this review emphasizes how ICTs have improved democratic engagement quality, efficiency, and transparency, b
Understanding Human-Centred AI: a review of its defining elements and a research agenda
The rapid advancements in artificial intelligence (AI) have ushered in a new era of innovative applications, while also prompting concerns regarding risks and adverse consequences. In light of the growing interest in comprehending AI's impact on society and its alignment with human values and needs, Human-Centred Artificial Intelligence (HCAI) has emerged as a potential approach to address questions and concerns. In this Systematic Literature Review, we aim to contribute to conceptual clarity ar
Challenging Cognitive Load Theory: The Role of Educational Neuroscience and Artificial Intelligence in Redefining Learning Efficacy
Background/Objectives: This systematic review integrates Cognitive Load Theory (CLT), Educational Neuroscience (EdNeuro), Artificial Intelligence (AI), and Machine Learning (ML) to examine their combined impact on optimizing learning environments. It explores how AI-driven adaptive learning systems, informed by neurophysiological insights, enhance personalized education for K-12 students and adult learners. This study emphasizes the role of Electroencephalography (EEG), Functional Near-Infrared
AI-driven triage in emergency departments: A review of benefits, challenges, and future directions
BACKGROUND: Emergency Departments (EDs) are critical in providing immediate care, often under pressure from overcrowding, resource constraints, and variability in patient prioritization. Traditional triage systems, while structured, rely on subjective assessments, which can lack consistency during peak hours or mass casualty events. AI-driven triage systems present a promising solution, automating patient prioritization by analyzing real-time data, such as vital signs, medical history, and prese
Artificial intelligence for individualized treatment of persistent atrial fibrillation: a randomized controlled trial
Although pulmonary vein isolation (PVI) has become the cornerstone ablation procedure for atrial fibrillation (AF), the optimal ablation procedure for persistent and long-standing persistent AF remains elusive. Targeting spatio-temporal electrogram dispersion in a tailored procedure has been suggested as a potentially beneficial alternative to a conventional PVI-only procedure. In this multicenter, randomized, controlled, double-blind, superiority trial, patients with drug-refractory persistent
The application of artificial intelligence in the field of mental health: a systematic review
INTRODUCTION: The integration of artificial intelligence in mental health care represents a transformative shift in the identification, treatment, and management of mental disorders. This systematic review explores the diverse applications of artificial intelligence, emphasizing both its benefits and associated challenges. METHODS: A comprehensive literature search was conducted across multiple databases based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses, including ProQu
Guiding AI in radiology: ESR’s recommendations for effective implementation of the European AI Act
This statement has been produced within the European Society of Radiology AI Working Group and identifies the key policies of the EU AI Act as they pertain to medical imaging. It offers specific recommendations to policymakers and the professional community for the effective implementation of the legislation, addressing potential gaps and uncertainties. Key areas include AI literacy, classification rules for high-risk AI systems, data governance, transparency, human oversight, quality management
A SEM–ANN analysis to examine impact of artificial intelligence technologies on sustainable performance of SMEs
This study investigates the impact of Artificial Intelligence (AI) adoption on the sustainable performance of small and medium-sized enterprises (SMEs). Employing a hybrid quantitative approach, this research combines Partial Least Squares Structural Equation Modeling (PLS-SEM) and Artificial Neural Networks (ANN) to examine the influence of various organizational, technological, and external factors on AI adoption. Key factors considered include top management support, employee capability, cust
Observation of an ultra-high-energy cosmic neutrino with KM3NeT
The detection of cosmic neutrinos with energies above a teraelectronvolt (TeV) offers a unique exploration into astrophysical phenomena1–3. Electrically neutral and interacting only by means of the weak interaction, neutrinos are not deflected by magnetic fields and are rarely absorbed by interstellar matter: their direction indicates that their cosmic origin might be from the farthest reaches of the Universe. High-energy neutrinos can be produced when ultra-relativistic cosmic-ray protons or nu
Inclusive education through technology: a systematic review of types, tools and characteristics
Technologies that contribute to inclusive education are digital tools and specialized devices that facilitate equitable access to learning for students with diverse abilities. Understanding these technologies allows for the personalization of teaching methods, the removal of barriers that limit participation for students with differences, and the promotion of a more accessible and equitable educational environment for all. This study aims to identify and analyze practices and technologies that f
Integrating Artificial Intelligence Agents with the Internet of Things for Enhanced Environmental Monitoring: Applications in Water Quality and Climate Data
The integration of artificial intelligence (AI) agents with the Internet of Things (IoT) has marked a transformative shift in environmental monitoring and management, enabling advanced data gathering, in-depth analysis, and more effective decision making. This comprehensive literature review explores the integration of AI and IoT technologies within environmental sciences, with a particular focus on applications related to water quality and climate data. The methodology involves a systematic sea
The integration of AI in nursing: addressing current applications, challenges, and future directions
Artificial intelligence is increasingly influencing healthcare, providing transformative opportunities and challenges for nursing practice. This review critically evaluates the integration of AI in nursing, focusing on its current applications, limitations, and areas that require further investigation. A comprehensive analysis of recent studies highlights the use of AI in clinical decision support systems, patient monitoring, and nursing education. However, several barriers to successful impleme
AI versus human-generated multiple-choice questions for medical education: a cohort study in a high-stakes examination
BACKGROUND: The creation of high-quality multiple-choice questions (MCQs) is essential for medical education assessments but is resource-intensive and time-consuming when done by human experts. Large language models (LLMs) like ChatGPT-4o offer a promising alternative, but their efficacy remains unclear, particularly in high-stakes exams. OBJECTIVE: This study aimed to evaluate the quality and psychometric properties of ChatGPT-4o-generated MCQs compared to human-created MCQs in a high-stakes me
AI Ethics: Integrating Transparency, Fairness, and Privacy in AI Development
The expansion of Artificial Intelligence in sectors such as healthcare, finance, and communication has raised critical ethical concerns surrounding transparency, fairness, and privacy. Addressing these issues is essential for the responsible development and deployment of AI systems. This research establishes a comprehensive ethical framework that mitigates biases and promotes accountability in AI technologies. A comparative analysis of international AI policy frameworks from regions including th
Recent Emerging Techniques in Explainable Artificial Intelligence to Enhance the Interpretable and Understanding of AI Models for Human
Recent advancements in Explainable Artificial Intelligence (XAI) aim to bridge the gap between complex artificial intelligence (AI) models and human understanding, fostering trust and usability in AI systems. However, challenges persist in comprehensively interpreting these models, hindering their widespread adoption. This study addresses these challenges by exploring recently emerging techniques in XAI. The primary problem addressed is the lack of transparency and interpretability in AI models
Unlocking precision medicine: clinical applications of integrating health records, genetics, and immunology through artificial intelligence
Artificial intelligence (AI) has emerged as a transformative force in precision medicine, revolutionizing the integration and analysis of health records, genetics, and immunology data. This comprehensive review explores the clinical applications of AI-driven analytics in unlocking personalized insights for patients with autoimmune rheumatic diseases. Through the synergistic approach of integrating AI across diverse data sets, clinicians gain a holistic view of patient health and potential risks.
Digital twins as global learning health and disease models for preventive and personalized medicine
Ineffective medication is a major healthcare problem causing significant patient suffering and economic costs. This issue stems from the complex nature of diseases, which involve altered interactions among thousands of genes across multiple cell types and organs. Disease progression can vary between patients and over time, influenced by genetic and environmental factors. To address this challenge, digital twins have emerged as a promising approach, which have led to international initiatives aim
FUTURE-AI: international consensus guideline for trustworthy and deployable artificial intelligence in healthcare
Despite major advances in artificial intelligence (AI) research for healthcare, the deployment and adoption of AI technologies remain limited in clinical practice. This paper describes the FUTURE-AI framework, which provides guidance for the development and deployment of trustworthy AI tools in healthcare. The FUTURE-AI Consortium was founded in 2021 and comprises 117 interdisciplinary experts from 50 countries representing all continents, including AI scientists, clinical researchers, biomedica
Higher education students’ perceptions of ChatGPT: A global study of early reactions
The paper presents the most comprehensive and large-scale global study to date on how higher education students perceived the use of ChatGPT in early 2024. With a sample of 23,218 students from 109 countries and territories, the study reveals that students primarily used ChatGPT for brainstorming, summarizing texts, and finding research articles, with a few using it for professional and creative writing. They found it useful for simplifying complex information and summarizing content, but less r
When LLMs meet cybersecurity: a systematic literature review
Abstract The rapid development of large language models (LLMs) has opened new avenues across various fields, including cybersecurity, which faces an evolving threat landscape and demand for innovative technologies. Despite initial explorations into the application of LLMs in cybersecurity, there is a lack of a comprehensive overview of this research area. This paper addresses this gap by providing a systematic literature review, covering the analysis of over 300 works, encompassing 25 LLMs and m
Examining inclusivity: the use of AI and diverse populations in health and social care: a systematic review
BACKGROUND: Artificial intelligence (AI)-based systems are being rapidly integrated into the fields of health and social care. Although such systems can substantially improve the provision of care, diverse and marginalized populations are often incorrectly or insufficiently represented within these systems. This review aims to assess the influence of AI on health and social care among these populations, particularly with regard to issues related to inclusivity and regulatory concerns. METHODS: W
Artificial intelligence using a latent diffusion model enables the generation of diverse and potent antimicrobial peptides
Artificial intelligence holds great promise for the design of antimicrobial peptides (AMPs); however, current models face limitations in generating AMPs with sufficient novelty and diversity, and they are rarely applied to the generation of antifungal peptides. Here, we develop an alternative pipeline grounded in a diffusion model and molecular dynamics for the de novo design of AMPs. The peptides generated by our pipeline have lower similarity and identity than those of other reported methodolo
Large Language Models for Chatbot Health Advice Studies
Importance: There is much interest in the clinical integration of large language models (LLMs) in health care. Many studies have assessed the ability of LLMs to provide health advice, but the quality of their reporting is uncertain. Objective: To perform a systematic review to examine the reporting variability among peer-reviewed studies evaluating the performance of generative artificial intelligence (AI)-driven chatbots for summarizing evidence and providing health advice to inform the develop
The factors affecting teachers’ adoption of AI technologies: A unified model of external and internal determinants
Abstract This study examines factors influencing teachers' intention to adopt Generative AI technologies in education by extending the Technology Acceptance Model (TAM). The proposed comprehensive model incorporates both external factors (exposure to AI information, information credibility, and institutional support) and internal factors (intrinsic motivation and self-efficacy). A survey of 400 teachers reveals that teachers’ exposure to credible AI information positively influences perceptions
The Future of Education: A Multi-Layered Metaverse Classroom Model for Immersive and Inclusive Learning
Modern education faces persistent challenges, including disengagement, inequitable access to learning resources, and the lack of personalized instruction, particularly in virtual environments. In this perspective, we envision a transformative Metaverse classroom model, the Multi-layered Immersive Learning Environment (Meta-MILE) to address these critical issues. The Meta-MILE framework integrates essential components such as immersive infrastructure, personalized interactions, social collaborati
Exploring the effects of artificial intelligence on student and academic well-being in higher education: a mini-review
The increasing use of artificial intelligence (AI) in higher education is reshaping how students engage with their academic and personal lives. However, the impact of AI on students' well-being remains underexplored. This mini-review synthesizes current literature to assess how AI affects student well-being, focusing on mental health, social interactions, and academic experiences. While AI offers benefits such as personalized learning, mental health support, and improved communication efficiency