Healthcare

Vision-language foundation models have shown strong potential in medical image analysis. Although foundation models for ultrasound imaging have recently emerged, the domain remains particularly challenging due to severe speckle noise, acquisition variability, and subtle anatomical boundaries, leading to high inter-observer variability. Existing CLIP-based models rely primarily on global image-text alignment, limiting their sensitivity to clinically decisive local structures. We propose SonoCLIP,

Role-semantic assignments provide priors over how heterogeneous agents may coordinate, but cooperative MARL systems instead settle on conventions through decentralized, non-stationary learning, with no guarantee that the resulting structure matches those priors. We study this translation gap between theory-informed role expectations and learned coordination structure through a diagnostic combining a role-routing matrix, formation sensitivity ($Δ_{\max}$), and gradient/occlusion attribution acros

Jointly learning to segment and classify medical images demands cross-task synergy, yet encoder-sharing architectures limit decoder reconstruction to task-private representations, permanently discarding the boundary cues and semantic priors each branch could supply to the other. This work introduces BTI-Net, which establishes bidirectional communication at every decoder level through two parallel pathways via Task Interaction Modules (TIM). Spatial boundary context is gated into the classificati

Ovarian cancer is frequently diagnosed at an advanced stage, making preoperative contrast-enhanced computed tomography (CT) central to staging and surgical planning; yet the scarcity of annotated imaging data, compounded by privacy regulations, limits the development of generalizable computational models in this domain. Text-conditioned 3D CT synthesis has shown promise, but existing pipelines depend on paired radiology reports and have been evaluated only on chest CT. We propose OvESyn (Ovarian

Rural health system Reid Health is using Abridge’s AI-powered documentation tech to reduce burnout among nurses. It appears to be working — after-shift charting is down by up to 45 minutes, and the RN vacancy rate has been cut more than in half, said Misti Foust-Cofield, Reid’s chief nursing officer. The post Documentation Tools Aren’t Just for Doctors: Inside Reid Health’s Deployment of Abridge’s Nurse Tech appeared first on MedCity News .

Speech-based cognitive impairment detection offers a noninvasive, accessible alternative to costly biomarker assays, yet transformer-based models remain clinically uninterpretable. We propose a multi-stage explainability framework that translates black-box transformer predictions into clinically grounded narratives by integrating SHapley Additive exPlanations (SHAP)-based token attribution, theory-informed linguistic features, and a four-stage LLM reasoning pipeline using LLaMA-3.1-70B-Instruct.

World models can predict future physical states, but prediction accuracy alone does not explain how physical information is organized and used inside their latent dynamics. We introduce a controlled diagnostic protocol for studying event-conditioned latent physical structure in passive object-state world models. The protocol tests whether hidden representations encode event-regime information, whether event contexts reweight non-exclusive physical field readouts, and whether field-aligned repres

By the authority vested in me as President by the Constitution and the laws of the United States of America, it is hereby ordered: Section 1. Purpose and Policy. Executive Order 14212 of February 13, 2025 (Establishing the President’s Make America Healthy Again Commission) established the Make America Healthy Again (MAHA) Commission, with an initial […] The post Advancing Regenerative Agriculture and Strengthening American Farm Resilience appeared first on The White House .

This week marks four years since Dobbs v. Jackson Women’s Health Organization overturned Roe v. Wade ’s constitutional protections for people seeking abortion care. Anniversaries are a moment to take stock, and over the last four years, EFF has seen firsthand how digital rights and reproductive rights have become increasingly intertwined. One major way this has happened: the fight over abortion has also become a fight over online speech and government censorship as a steady stream of proposed la

Biotech executives reveal concerns over Chinese biotech, the profitability of AI, and the durability of Trump's drug price moves.

The MAHA movement has been promoting the plant-based substance ibogaine as a remedy for opioid addiction, despite the lack of clinical trials on its safety and efficacy. One physician who practices addiction medicine discusses the risks of ibogaine and argues for the need to support proven treatments.

AI healthcare chatbots are increasingly used to support health information seeking and self-management, yet their performance and impact on users remains to be studied. This study examines over 15,000 user reviews from 59 AI healthcare chatbot apps to explore how these systems function in everyday informational and emotional contexts. Topic modeling and interpretive analysis identify three recurring breakdowns: access barriers and service unreliability, user experience and interaction quality, a

Large language models (LLMs) are increasingly being integrated into mental health support tools and other psychologically sensitive conversational applications. In such settings, behavioral stability and consistency are important for trustworthy human-AI interaction. However, semantically similar concerns can be presented through different contextual framings, potentially eliciting different model responses. Such framing-sensitive variability may challenge user expectations regarding system beha

Empirical Bayes (EB) estimators can match the first-order asymptotic risk of maximum likelihood (ML) while behaving very differently at second order: recent excess mean squared error (XMSE) analysis shows that kernel-based EB estimation may be worse than ML when the kernel is poorly aligned with the true parameter. This paper turns that diagnostic into a design principle. We propose an XMSE-aware mixed estimator that interpolates between ML and EB shrinkage. Its fixed-weight XMSE is a scalar qua

Large language models can serve as capable long-horizon agents, but their out-of-distribution (OOD) generalization remains weak. We identify a key source of this failure as task insensitivity: when faced with similar but distinct tasks, models might apply patterns learned during training and fail to solve the task at hand. We show that models often continue with actions aligned with the original task even when the instruction is semantically corrupted and cannot be directly answered. We further

Automatic Speech Recognition (ASR) is increasingly used to document clinical encounters, yet its reliability in multilingual and demographically diverse Indian healthcare context remains largely unknown. In this study, we first conduct the systematic audit of ASR performance on real-world psychiatric interview data spanning Kannada, Hindi and Indian English, comparing eight state-of-the-art models including IndicWhisper, WhisperLargeV3, Sarvam, GoogleS2T, Gemma3n, OmniLingual, Vaani, and Gemini.

Developing robust artificial intelligence models for 4D (3D + time) medical imaging is constrained by limited annotated data, inter-device domain shifts, and privacy restrictions. To address this, we propose a 4D controllable generative framework for anatomically consistent data augmentation. A semi-supervised variational autoencoder learns a compact latent representation of anatomical volumes while jointly predicting aligned segmentation masks in a unified framework. Anatomical structure is the

Skin lesion segmentation is a key task in computer-aided dermatological diagnosis, where accuracy directly impacts downstream analysis and disease classification. However, dermoscopic images are challenging due to blurred boundaries, low contrast, large shape variations, and artifacts such as hair and shadows. Recently, diffusion models have shown strong performance in medical image segmentation thanks to their progressive denoising and distribution modeling capabilities. Nevertheless, existing

Current VLM evaluations often conflate language priors with genuine spatial reasoning. To address this, we introduce CRISP, a novel structural-diagnostic evaluation paradigm that assesses visual spatial intelligence through consistency, the alignment between implicit perception and explicit reasoning. Unlike traditional black-box QA, CRISP utilizes metric 3D Scene Graphs and an oracle intervention protocol to decouple latent reasoning capabilities from perceptual bottlenecks. This granular diagn

Medical AI remains organized around isolated models, whereas care requires accountable capabilities that persist across time. We define clinical AI skills and propose the Clinical Harness, a runtime governance architecture that registers, orchestrates, constrains and monitors them. Using osteoporosis as an exemplar, we show how knowledge-driven, data-driven and physics-enhanced skills can support lifecycle care and provide a governed substrate for future medical agents.

Loneliness is a pressing global health issue, yet traditional interventions often fall short due to scalability limitations and the individualized experiences of loneliness. The rise of generative artificial intelligence (AI) has enabled synthetic relationships (SRs)—ongoing associations with AI companions designed to simulate human-like social bonds. SRs offer, among other aspects, constant availability, adaptability, and emotional responsiveness, which potentially address loneliness. However,

Agentic benchmarks have emerged across general-purpose and domain-specific settings, including finance, coding, law, and drug discovery, yet energy-domain evaluations remain largely limited to static knowledge recall. This is a critical gap for a sector that requires live data retrieval, specialized regulatory and market knowledge, and multi-step quantitative reasoning under real-world constraints. We present an empirical study of tool-augmented LLM agents on real-world energy market analytics t

Autonomous AI agents may begin to perform consequential, irreversible actions such as clinical prescribing and production software deployment. This paper observes that human institutions have governed powerful autonomous actors not by monitoring their reasoning but by requiring independently attested evidence at the point of consequential action. We formalise this institutional pattern as a computational governance model for AI agent systems. Under the proposed model, an agent retains full auton

A new study published in Nature uses artificial intelligence to identify people at high risk for sudden cardiac death, and pinpoints a possible reason.

Early identification of speech sound errors in children is often limited by access to specialists, motivating lightweight screening tools that can operate outside the clinic. We present a screening pipeline for Polish-speaking children focused on sibilant substitutions, coupling a wav2vec2-based CTC token recognizer with alignment-based error typing and a template-grounded caregiver assistant for screening, not diagnosis. On a held-out test set of 10 unseen children comprising 559 utterances, th

Digital surveillance does much more than steal data. It inflicts deep human wounds; it stops people from safely developing and expressing their identities, breeds trauma that can last for generations, and fractures the human mind.

Modern coding agents pair LLM generators with various tools, including cheap diagnostics and expensive verifiers. The tool-use decisions are typically governed by orchestrators that often use fixed rules and ignore uncertainty. We formulate orchestration as cost-sensitive sequential hypothesis testing: a Bayesian controller maintains a belief over candidate correctness and dynamically decides whether to gather more evidence, refine the candidate, verify it, or stop. Across six generators and nin

Retrieval-augmented generation (RAG) in clinical settings increasingly requires multilingual retrieval against predominantly English evidence corpora. Multilingual medical retrieval demands three capabilities: cross-lingual alignment, concept discrimination, and evidence retrieval. However, existing benchmarks evaluate these only in isolation, leaving the interaction between biomedical expertise and multilingual coverage unmeasured. We introduce MMed-Bench-IR, a benchmark designed to disentangle

While Vision-Language Models (VLMs) show great promise in volumetric medical report generation, they frequently suffer from visual hallucinations and a lack of grounding in 3D CT data. Current Supervised Fine-Tuning (SFT) and Reinforcement Learning (RL) strategies typically optimize text fidelity alone, essentially rewarding correct diagnoses derived from language priors rather than genuine visual perception. To address this, we propose cross-view aligned Evidence-driven Multimodal Reinforcement

General-purpose large language models (LLMs) are increasingly used for mental health-related conversations, yet safety guardrails remain inadequate and inconsistent across clinical conditions. This study evaluates eight proprietary LLMs across 16 DSM-5 conditions using four adversarial attack variants, introducing an eight-dimension harm taxonomy and a multi-dimensional evaluation framework. Results show that safeguards hold reliably only for suicide and self-harm, while conditions such as eatin

Tensor decomposition of donor $\times$ cell-type $\times$ gene single-cell data recovers \emph{multicellular programs}: coordinated axes of inter-individual transcriptional variation that span cell types and stratify disease. Yet immune single-cell atlases are increasingly multi-institution, multi-ancestry, and governed, so patient cells often cannot be pooled. We present a federated estimator: each site computes a local program subspace, and a coordinator merges these by stacked SVD under feder

Medical vision-language models (VLMs) such as BiomedCLIP generalize broadly, but adapting them to a clinical service is as much a safety problem as an accuracy one. Updating a deployed model for a new imaging modality can fail silently in two ways that harm patients: it can forget modalities it already handled (catastrophic forgetting), and it can drift from its trustworthy pretrained prior toward modality-specific shortcuts. We study parameter-efficient continual adaptation through these two pr

Recent advances in robot world models enable synthetic video generation for embodied prediction and planning. However, evaluating these videos is challenging: visually realistic outputs often violate physical laws, temporal consistency, or task logic, while conventional metrics and monolithic Vision-Language Model (VLM) judges fail to generalize or provide precise diagnostic value. We present RoboGaze, a training-free, multi-agent VLM framework that provides structured, interpretable evaluation

Alignment tuning is meant to make harmful-request refusal robust, yet this safety behavior can be erased by a small set of benign fine-tuning examples. This is a deployment risk for open-weight models because a checkpoint can pass refusal tests at release time and later lose refusal under low-cost downstream fine-tuning. Prior work has established these refusal failures, but existing studies do not show how to detect this fragility in the aligned model itself before an attack or fine-tuning inte

We present JEDEL, a framework for generating synthesis-ready DNA-encoded libraries (DELs) directly from three-dimensional pharmacophore representations of active ligands. JEDEL is the first model to map pharmacophore interaction patterns to actionable, scalable synthesis instructions, enabling the design of targeted libraries comprising potentially millions of molecules. Unlike existing generative approaches that produce virtual compounds requiring downstream synthesis planning, JEDEL operates w

Foundation models have achieved remarkable performance across medical question answering, imaging, and electronic health record (EHR) tasks, yet reliable clinical deployment remains challenging due to limited interpretability, vulnerability to distribution shift, and weak alignment with clinician reasoning. We argue that these limitations arise because existing approaches prioritize representation learning while treating patient comparison as an emergent property rather than a primary source of

Medical image re-identification (MedReID) enables longitudinal patient linkage but remains vulnerable to shortcut learning and often produces decisions that clinicians cannot audit against named anatomy. We propose Graph-of-Differences (GoD), which grounds identity comparisons in explicit anatomical structure. Each image is represented as an anatomy graph whose nodes correspond to named anatomical regions; given an image pair, soft node correspondence is established, and differences are computed

Medical Vision-Language Models (Med-VLMs) achieve strong expert-level performance, yet their ability to generate patient-accessible descriptions remains underexplored. With the 21st Century Cures Act now mandating immediate patient access to diagnostic imaging results, evaluating whether Med-VLMs can bridge this Expert-Lay Gap is both urgent and clinically consequential for patient education and shared decision-making. To this end, we introduce MedLayXPlain, the first large-scale multimodal benc

EEG foundation models can learn generalizable representations from large-scale EEG corpora to enable single-backbone transfer across diverse clinical and brain-computer interface tasks. Existing models typically discretize the continuous multi-channel EEG waveform into patches or codebook tokens and train a transformer with masked self-supervision. Recognizing that this discretization fragments continuous brain rhythms and obscures fine-grained temporal dynamics, we present B[FM]$^2$(Brain Found

Clinical NLP increasingly relies on electronic health record (EHR) data to detect suicidal behaviors, treating clinical documentation as more reliable ground truth than social media. We argue that this framing obscures how EHR-based suicidality datasets encode a particular operationalization of suicidality, shaped by who authors the data, how episodes are bounded, and how ambiguity is resolved. We ground this argument in a case study of the ScAN dataset, built over MIMIC-III clinical notes. We s