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From mechanistic models to artificial intelligence: exploring the potential of digital twins in geriatric oncology

This survey explores how machine learning and artificial intelligence (AI) can be integrated with mechanistic models to create more accurate, dynamic, predictive, and personalized representations of biological systems, commonly referred to as digital twins (DTs). Mechanistic models, such as pathway-based Boolean or differential equation frameworks, provide interpretable insights into biological processes; however, calibrating these models to represent individual variability across large, heterog
Frontiers in Artificial Intelligence 8d ago Biotech

HIDANet: a lightweight deep learning framework for Vannamei post-larval stage classification and morphometric estimation with background bias validation

IntroductionQuality control of hatchery production relies on accurate developmental staging of the Pacific white shrimp Litopenaeus vannamei post-larvae (PL), but current methods rely on subjective manual visual evaluation that leads to observer bias and inconsistency.MethodsIn this study, the Hierarchical Isotropic Dense Attention Network (HIDANet) has been introduced, a lightweight convolutional neural network with 0.033M parameters that learns to classify seven post-larval stages (PL5–PL12) i
Frontiers in Artificial Intelligence 8d ago Bias & fairness

An explainable end-to-end computer vision pipeline for detection, segmentation, and reconstruction of occluded weapons in forensic imagery

IntroductionImages from crime scenes often show partially concealed weapons due to obstructions such as hands and clothing, as well as surveillance camera limitations, which affect the efficacy of traditional detection methods. This work proposes an explainable forensic pipeline for occluded weapons detection, segmentation, and reconstruction.MethodsThe proposed framework integrates RT-DETR-L, a transformer-based weapon detection model; MobileSAM for zero-shot segmentation of visible weapon regi
Frontiers in Artificial Intelligence 8d ago PrivacyMilitary & security

The VIBE-HI framework: a conceptual model for evaluating vibe coding appropriateness, quality, and safety in health informatics

BackgroundVibe coding—generating software through natural-language prompts to large language models without reviewing the underlying code—has moved rapidly from consumer technology into peer-reviewed clinical applications. By early 2026, clinicians had published vibe-coded teaching tools, a validated clinical nomogram, and an end-to-end omics platform built in under 10 minutes for under two dollars. Collins Dictionary named vibe coding its 2025 Word of the Year. No governance framework currently
Frontiers in Artificial Intelligence 8d ago RegulationHealthcare

Hybrid fuzzy C-means and deep learning framework for intelligent fault classification in solar PV systems

Photovoltaic (PV) systems have proven themselves to be a viable alternative energy source; however, there are multiple faults related to PV systems which cause energy losses and low efficiencies. Manual or rule-based algorithms are traditionally used for fault diagnosis, which are not efficient and unsuitable for real-time applications. In this paper, a novel hybrid intelligent classification system for PV fault detection is proposed by integrating Fuzzy C-Means (FCM) clustering and Deep Learnin
Frontiers in Artificial Intelligence 8d ago HealthcareEnvironment

The Human-AI Substitution Principle: When will you be replaced by AI in your organization?

Artificial Intelligence (AI) is rapidly transforming organizations, raising a fundamental organizational and economic question: when will a human employee be replaced by AI? We present an analytical model for studying Human--AI Task Allocation (HAT) in hierarchical organizations. A central feature of the HAT model is that it formally encodes the economic asymmetry between human skill acquisition and AI capability scaling. The HAT model allows us to derive how risk-adjusted costs, skills, organiz
arXiv 8d ago

HARP: The Human--AI Research Platform

Large language models (LLMs) have shifted human--computer interaction from `traditional'' interface journeys toward more conversational exchanges. Researchers studying HCI and UI use moderated usability sessions, interviews, surveys, transcript analysis, and static prototypes. However, static prototypes provide limited opportunities to study interaction with live AI systems or systematically control how an LLM behaves across participants and scenarios. Conversation transcripts reveal little abou
arXiv 8d ago

Operational Identity: A Finite Audit of Declared and Implemented Rules of Sameness

A record system declares when two records refer to the same entity, occurrence, scope, or rule. Its disclosed implementation mechanisms induce a corresponding operational identity relation. The declared and implemented relations may diverge systematically without producing a provenance gap or detectable contradiction. A system can apply, consistently and with every record individually correct, a rule of sameness that no artifact declares. This paper formalizes that implemented relation. A declar
arXiv 8d ago Transparency

Gender Inclusivity and Exclusivity in US Hospitals’ Online Obstetrics, Labor and Delivery, and Pregnancy-Related Resources: Cross-Sectional Study

Background: Research on transgender people’s health, particularly in reproductive health, has expanded exponentially over the past decades. However, previous studies frequently highlight perceived inaccessibility and gender-exclusivity of reproductive and perinatal care for transgender people. Objective: This observational study used a cross-sectional content analysis to examine online obstetrics, labor and delivery, and pregnancy-related materials from a purposive sample of 178 online hospital
JMIR (Journal of Medical Internet Research) 8d ago Jobs & economyHealthcare

Transition-Related Potentials as Markers of Narrative Comprehension in Continuous EEG

Harnessing the potential of electroencephalography (EEG) for brain research is fundamentally limited by intrinsic noise and the diffuse projection of brain-generated activity over the scalp. The standard event-related potential (ERP) paradigm addresses this limitation by relying on repeated independent trials, albeit at the cost of moving away from naturalistic experimental conditions. As a more naturalistic alternative, we collected continuous EEG while participants watched short films and extr
arXiv 8d ago

Efficacy of Various Virtual Reality Exposure Therapies for Chronic Low Back Pain: Systematic Review and Network Meta-Analysis

Background: Chronic low back pain (CLBP) is a major global health challenge. While nonpharmacological therapies are recommended, patient compliance is often hindered by kinesiophobia. Virtual reality (VR) offers an immersive, distraction-based approach, but the comparative effectiveness of different VR modalities remains unclear. Objective: The aim of the study is to compare and rank the efficacy of different VR-based training modalities on pain intensity, disability, and kinesiophobia in patien
JMIR (Journal of Medical Internet Research) 8d ago RegulationHealthcare

Improving the performance of an ASV system using hybrid speech features

The growing need for secure and convenient authentication methods has led to the increasing popularity of biometric solutions. In addition to traditional and popular methods, such as fingerprint or iris scanning, voice-based approaches are also employed. User identity verification based on voice is conducted using Automatic Speaker Verification (ASV) systems. Despite their many advantages, these systems are sensitive to various types of attacks and acoustic noises, which can reduce verification
arXiv cs.HC 9d ago Privacy

U-CFR: Uncertainty-Guided Cascade Forward Refinement for Interactive Segmentation

Interactive image segmentation is critical for efficient image annotation; however, existing methods often require many corrective clicks or rely on passive refinement schemes that converge slowly. We propose Uncertainty-Guided Cascade Forward Refinement (U-CFR), a novel inference-time framework that enables models to autonomously self-correct after each user interaction. U-CFR introduces a boundary-aware uncertainty score that fuses segmentation uncertainty, contour gradients, and explicit edge
arXiv 9d ago

A Framework for Reputation Aware Uninorm-driven Consensus Algorithms for Blockchain Networks

The operation of blockchain is governed by consensus algorithms (CA). Several consensus mechanisms require significant computational power, while others necessitate high amounts of stakes to select the participant to validate and verify the transactions in the block, leading to centralisation of power and participant exclusion. This paper proposes a novel methodology to address these issues in reputation-based consensus algorithms by studying the reputation behaviour of the validator using intui
arXiv 9d ago

OpenForgeRL: Train Harness-native Agents in Any Environment

Modern AI agents rely on elaborate inference harnesses such as Claude Code, Codex, and OpenClaw to drive multi-turn reasoning, tool use, and access to external systems. While powerful, these complex harnesses also make agents hard to train end-to-end with open infrastructure, whose SFT/RL stacks cannot natively express stateful, multi-process harness inference. To address this, we present OpenForgeRL, an open-source framework for training harness-based agents end-to-end in diverse environments.
HuggingFace Daily Papers 9d ago Agents & autonomyEnvironment

K12-KGraph: A Curriculum-Aligned Knowledge Graph for Benchmarking and Training Educational LLMs

Large language models are increasingly used in K-12 education, but existing benchmarks mainly test exam question answering rather than understanding how curriculum knowledge is structured and visually presented. We call this capability curriculum cognition. It covers prerequisite chains, concept taxonomies, experiment-concept links, pedagogical sequencing, and visual grounding. We introduce K12-KGraph, a curriculum-aligned knowledge graph extracted from official People's Education Press textbook
HuggingFace Daily Papers 9d ago Children & education

Sample-Efficient Learning from Agent Experience

Real-world agent learning is often constrained by costly environment interactions, such as running time-consuming experiments or obtaining human feedback. In-context learning offers a highly sample-efficient way for agents to learn from their own interaction histories, but its gains disappear once that experience is removed from the context. Separately, context distillation provides a mechanism for internalizing contextual information into model weights. However, applying it to agents' interacti
HuggingFace Daily Papers 9d ago Agents & autonomyEnvironment

Show, Don't Tell: Evaluating Spatial Cognition in Generative Pixels Rather Than LLM Text

Spatial intelligence is essential for agents to move from static semantic understanding toward interacting with the physical world. Many spatial tasks are grounded in continuous visual scenes, where locations, regions, and paths are more naturally expressed by pointing, marking, or drawing than by reporting precise coordinates or discrete textual symbols. Yet existing spatial reasoning benchmarks usually require coordinates, options, or text, creating an answer-interface mismatch for image-gener
HuggingFace Daily Papers 9d ago Agents & autonomy

Visual Contrastive Self-Distillation

On-policy self-distillation (OPSD) is promising as it removes the external teacher required by on-policy distillation (OPD), yet it still needs asymmetric information between teacher and student to ensure that the self-teacher provides a stronger learning signal than the student. Existing methods create this asymmetry either through privileged answers or visual evidence. We ask whether both can be removed, yielding a simpler form of OPSD driven purely by input conditioning. For this purpose, we
HuggingFace Daily Papers 9d ago RegulationChildren & education

AREX: Towards a Recursively Self-Improving Agent for Deep Research

Deep research requires agents to find answers that jointly satisfy multiple constraints. Discovering such answers is costly, whereas verifying a candidate can often be decomposed into tractable constraint-wise checks. This discovery--verification asymmetry suggests that a research agent should do more than simply search longer: it should recursively improve its current answer by verifying intermediate results and using the partially verified state to guide subsequent refinement. We introduce ARE
HuggingFace Daily Papers 9d ago Agents & autonomy

Tencent WorkBuddy Bench: A Multi-Domain Coding-Agent Benchmark with Contamination-Resistant Task Construction

We introduce Tencent WorkBuddy Bench, a multi-domain evaluation suite for coding agents; this report documents its construction methodology, scoring protocol, and a cross-model leaderboard. At its core is a unified evaluation framework for constructing and running distribution-informed coding-agent tasks across four work domains - Code, Web, Office, and Security. Rather than adapting public issue text, every task is reverse-engineered from a real commit, pull request, or business scenario and re
HuggingFace Daily Papers 9d ago Agents & autonomy

TableVerse: A Large-scale Tabletop Dataset with Real-world Grounded Layouts for Generalizable Manipulation

The development of generalizable robotic manipulation policies is inherently bounded by the availability of large-scale, high-fidelity scene data. While recent automated synthesis methods attempt to bridge this gap via text-to-layout hallucination or simplified procedural generation, they frequently suffer from physical implausibility and fail to capture the complex, dense clutter of actual human environments. In this paper, we introduce TableVerse, a fully automated Real2Sim pipeline that shift
HuggingFace Daily Papers 9d ago Agents & autonomyEnvironment

Streaming Multi-Agent Autoregressive Diffusion Model with World State Registers

Multi-agent interactive world models should not only generate consistent observations, but also maintain world states that persist across agents and evolve across views. Existing autoregressive video diffusion pipelines carry forward observation history as conditioning context, which makes shared state difficult to maintain in multi-agent and multi-view settings. We present WorldWeaver (W^2), a streaming multi-agent video diffusion model that augments rollout with cross-agent world state registe
HuggingFace Daily Papers 9d ago Agents & autonomy

ICAE-Bench: Evaluating Coding Agents as Interactive Project Builders

The recent emergence of vibe-coding workflows is changing what coding agents are expected to do. Instead of merely completing code under fully specified instructions, agents are increasingly expected to transform incomplete product intent into working software by combining various abilities including planning, requirement clarification, tool use, debugging, and repository-level construction. Yet existing benchmarks have not fully caught up with this shift, evaluating agents on static, fully spec
HuggingFace Daily Papers 9d ago Agents & autonomy

Agentic Context Management: Solving Agent Memory and Cost by Treating Them as Lifecycle and Architecture Problems

Production AI agents' failures are less often due to an inability to reason well and more often because they cannot manage what is in their reasoning context: conversation histories, large prompts, large tool definitions, and ballooning tool outputs. Agents drown in their own accumulating history while paying a token cost that grows every turn, producing missing recalls within and across conversations. The incumbent response treats this as a storage-and-retrieval problem. We argue that framing i
HuggingFace Daily Papers 9d ago Agents & autonomy

Language Models Embody and Amplify Human Cognitive Distortions: What Is to Be Done?

Human judgment is fundamentally prone to error. A promise of AI is that it will rid decisions of bias and ensure a fairer and safer world for all. Yet research unequivocally demonstrates that LLMs exhibit consequential sociocognitive biases. We alert readers that bias in AI (a) is covert and ironically a feature of alignment goals, (b) is not merely a mirror, but an amplifier of human bias, (c) intensifies across model generations, and (d) even transmits bias to humans. Given the potentially sei
arXiv 9d ago Bias & fairnessSafety & alignment

Spatially Grounded Concept Bottleneck Models for Trustworthy Breast Ultrasound Diagnosis

Concept Bottleneck Models provide interpretable-by-design predictions by mediating diagnosis through human-understandable concepts, but in medical imaging, their trustworthiness is often limited by the quality and granularity of available supervision. In particular, predicted concept activations can be driven by irrelevant regions, leading to spatially unfaithful explanations. We study a data-centric spatially grounded Concept Bottleneck Model (SG-CBM) that leverages coarse lesion delineations a
arXiv 9d ago Healthcare

Evaluation Frameworks for Clinical AI Incorporating Validation Strategies, Real-World Applicability, and Ethical Principles: Scoping Review

Background: AI shows substantial potential in health care; however, the absence of standardized evaluation frameworks limits its safe and effective clinical implementation because of inconsistent validation requirements and fragmented ethical principles. Existing guidelines vary in structure, methodological rigor, and ethical integration, creating uncertainty. Objective: This study aimed to systematically map, characterize, and critically analyze existing evaluation frameworks for clinical AI, f
JMIR (Journal of Medical Internet Research) 9d ago Healthcare

Enhancing Attack Detection Capabilities in BACnet/IP Networks Using Machine-Learning Models

Building Automation Systems (BAS) manage critical building functions using protocols such as BACnet/IP, yet defenders have limited tooling and few labeled datasets for detecting BACnet-specific attacks. This work addresses these gaps through three contributions. First, CISA's Zeek BACnet parser is modified to produce a unified per-packet log, simplifying feature engineering for machine-learning (ML) pipelines. Second, a simulated BACnet/IP testbed is developed using bacpypes3 to model a small co
arXiv cs.CR (AI security) 9d ago Jobs & economy

Towards Miniature Humanoid Tele-Loco-Manipulation Using Virtual Reality and Reinforcement Learning

Full-sized humanoid robot capabilities have grown exponentially in recent years, aiming towards general-purpose deployment in human environments. A popular control method used by manufacturers utilizes Virtual Reality for upper-body teleoperation and Reinforcement Learning for lower-body balance and locomotion control. As a result, a single remote operator can see, manipulate, and navigate about a real, distant physical environment. This powerful control stack is often relegated to expensive ful
arXiv cs.HC 9d ago Agents & autonomyEnvironment

FMRP-LEAN: A HIPAA-Compliant AI-Augmented LIMS Architecture for End-to-End Clinical Assay Workflow Optimization

Clinical biomarker workflows in translational research settings often rely on spreadsheet-driven tracking, manual quality control (QC) reconciliation, and loosely integrated systems, resulting in limited state visibility, delayed reporting, and increased operational risk. These challenges are particularly pronounced in multi-day assays such as Luminex-based quantification of Fragile X Messenger Ribonucleoprotein (FMRP), where HIPAA-compliant data governance, deterministic workflow progression, a
arXiv 9d ago RegulationPrivacy

Train the Model, Not the Reader: Decodability Supervision for Verifiable Activation Explanations

Natural-language autoencoders score explanations of hidden activations by reconstruction: an explanation is deemed faithful if the activation can be regenerated from it. The test is structurally insensitive to individual false claims: if flipping a claim does not change the reconstruction, the claim is never penalized. We show the test is passed in two ways, neither faithful. On a released Qwen-2.5-7B verbalizer, explanations reconstruct well above chance while ~2% of specific claims are reconst
arXiv 9d ago

PG-KINN: A Physics-Informed Petrov-Galerkin Kolmogorov-Arnold Network for Solving Forward and Inverse PDEs

Physics-informed learning of partial differential equations (PDEs) has been dominated by multilayer perceptrons (MLPs), whose spectral bias and dense parameterization limit both accuracy and interpretability. Kolmogorov Arnold Networks (KANs) mitigate these limitations because their learnable spline activations are structurally aligned with the piecewise-polynomial bases of classical discretizations. However, the way a PDE is cast into a loss functional is as decisive as the choice of approximat
arXiv cs.LG 9d ago Bias & fairnessSafety & alignment

Statevector-Referenced Geometry Survival of a Four-Qubit ZZ Quantum Kernel on IBM Quantum Hardware: A Fixed-Subset Diagnostic Across Three Execution Configurations

Quantum-kernel methods encode a dataset's geometry in a Gram matrix, so learning claims on hardware kernels assume the intended geometry survives execution. We measure that survival for one frozen four-qubit ZZ feature-map kernel on $N=24$ real indoor air-quality windows, reconstructed on ibm_fez (1024 shots per circuit) under baseline, dynamical decoupling alone, and gate twirling alone, each a single non-interleaved job. Every configuration returned a complete, finite, positive-semidefinite Gr
arXiv cs.LG 9d ago Jobs & economyHealthcare

Online Variance Reduction for Domain Adaptation on Streaming Data

This paper studies the problem of stochastic variance reduction (SVR) for the maximum mean discrepancy (MMD) and correlation alignment (CORAL) loss functions. Although various offline SVR algorithms for these losses have been proposed, these are incompatible with online, distributed, or incremental learning settings. This paper presents Adaptive vaRiance Reduction via Online reWeighting (ARROW), the first online SVR algorithm for the MMD and CORAL for streamed data. The method maintains moving a
arXiv cs.LG 9d ago Safety & alignment

International PhD students to face strict limits on time in the US

Overturning a decades-old policy, the US government will soon limit international students to no more than four years in the United States unless they can secure an extension from the US government.
Nature Machine Intelligence 9d ago RegulationChildren & education

Upcoming Programmes and Events

*Nanyang Executive Education reserves the right to change the date, venue and mode of delivery due to unforeseen circumstances or prevailing government advisories.
NTU Singapore AI 9d ago Children & education

Variance-reduced Domain Adaptation using Paired Sampling

Correlation alignment and the maximum mean discrepancy are two widely used distribution-matching frameworks for unsupervised domain adaptation (UDA). However, high variance in these losses has been shown to undermine their effectiveness in minibatch optimisation settings. Furthermore, the losses lack finite-sum structure, which renders them incompatible with classical stochastic variance reduction (SVR) methods. This paper proposes Paired Sampling for Domain Adaptation (PSDA), a novel SVR techni
arXiv cs.LG 9d ago Safety & alignment

Generative AI floods and dilutes the market for books

Generative AI can produce book-length works of fiction at near-zero cost. These books are often dismissed as low-quality ``slop'' that buyers will ignore, and are assumed to carry little commercial weight. We test that assumption with full-text AI detection across 14,419 self-published genre-fiction books sold on Amazon from 2023 to 2026, matched to daily sales records through June 2026. None of these books disclose whether or not they contain AI-produced content. We find that books for which we
arXiv 9d ago

Closing the Lab-to-Store Gap: A Data-Efficient Post-Training and Experience-Driven Learning VLA Framework for Retail Humanoids

Closing the gap between benchmark performance and reliable real-world operation remains a central challenge for Vision-Language-Action (VLA) humanoid robots, which must handle execution errors, distribution shifts, and environmental variability. This paper presents DEED (Data-Efficient Post-Training and Experience-Driven Learning), a systems-level approach evaluated on a supermarket chip-restocking task using a Unitree G1-Edu humanoid robot and the GR00T N1.6 foundation model. DEED comprises thr
arXiv 9d ago Agents & autonomyEnvironment
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