AI ethics on Saturday, 10 January 2026

High-throughput proteomics is critical for understanding biological processes, enabling large-scale studies such as biomarker discovery and systems biology. However, current mass spectrometry technologies face limitations in speed, sensitivity, and scalability for analyzing large sample cohorts. The Thermo Scientific Orbitrap Astral Zoom mass spectrometer (MS) was developed to address these limitations by improving acquisition speed, ion utilization, and spectral processing, which are all essent

INTRODUCTION: This study evaluated the effectiveness of Moderna's updated mRNA-1273 vaccine targeting the KP.2 variant, compared to people who did not receive any 2024-2025 COVID-19 vaccine, in preventing COVID-19-associated hospitalizations and medically-attended COVID-19 among adults aged ≥ 18 years in the United States during the 2024-2025 season. METHODS: Data were extracted from linked administrative healthcare claims and electronic health records (EHR) for vaccinations from 23 August 2024

3D Concrete Printing (3DCP) is reshaping construction by enabling automated fabrication, reducing material waste, and supporting more sustainable building solutions. This study presents a bibliometric and thematic analysis of global 3DCP research from 2015 to April 2025 using data from the ScienceDirect and Dimensions databases. VOSviewer was employed to map research trends, country collaborations, and thematic clusters. The review identifies four main focus areas: (I) advancements in 3DCP techn

To compare the diagnostic performance of a subscription-based medical large language model (LLM) certified as a medical device (Prof. Valmed), a subscription-based general-purpose LLM (ChatGPT-5 Thinking), and a freely accessible medical LLM (OpenEvidence). Sixty vignettes covering rare rheumatic diseases and differential diagnoses were entered using a standardized prompt to generate five top diagnoses and respective diagnostic probabilities. Blinded rheumatologists categorized suggested diagnos