Research (12)
Drug repurposing: a systematic review on root causes, barriers and facilitators
BACKGROUND: Repurposing is a drug development strategy receiving heightened attention after the Food and Drug Administration granted emergency use authorization of several repurposed drugs to treat Covid-19. There remain knowledge gaps on the root causes, facilitators and barriers for repurposing. METHOD: This systematic review used controlled vocabulary and free text terms to search ABI/Informa, Academic Search Premier, Business Source Complete, Cochrane Library, EconLit, Google Scholar, Ovid E
An Overview of Artificial Intelligence Ethics
Artificial intelligence (AI) has profoundly changed and will continue to change our lives. AI is being applied in more and more fields and scenarios such as autonomous driving, medical care, media, finance, industrial robots, and internet services. The widespread application of AI and its deep integration with the economy and society have improved efficiency and produced benefits. At the same time, it will inevitably impact the existing social order and raise ethical concerns. Ethical issues, su
Review of Artificial Intelligence and Machine Learning Technologies: Classification, Restrictions, Opportunities and Challenges
Artificial intelligence (AI) is an evolving set of technologies used for solving a wide range of applied issues. The core of AI is machine learning (ML)—a complex of algorithms and methods that address the problems of classification, clustering, and forecasting. The practical application of AI&ML holds promising prospects. Therefore, the researches in this area are intensive. However, the industrial applications of AI and its more intensive use in society are not widespread at the present ti
Metaverse beyond the hype: Multidisciplinary perspectives on emerging challenges, opportunities, and agenda for research, practice and policy
The metaverse has the potential to extend the physical world using augmented and virtual reality technologies allowing users to seamlessly interact within real and simulated environments using avatars and holograms. Virtual environments and immersive games (such as, Second Life, Fortnite, Roblox and VRChat) have been described as antecedents of the metaverse and offer some insight to the potential socio-economic impact of a fully functional persistent cross platform metaverse. Separating the hyp
Trust in blockchain-enabled exchanges: Future directions in blockchain marketing
Abstract Prior research typically positions blockchain technology as enabling a trustless exchange environment without specifically investigating how blockchain technology provides trust and what makes the data in a blockchain “tamperproof” and “immutable.” This article serves to address these research gaps by conducting semi-structured interviews with 18 informants who have had at least three years of project experience with blockchain-enabled exchanges. Our findings uncover three unique aspect
A Survey on the Fairness of Recommender Systems
Recommender systems are an essential tool to relieve the information overload challenge and play an important role in people’s daily lives. Since recommendations involve allocations of social resources (e.g., job recommendation), an important issue is whether recommendations are fair. Unfair recommendations are not only unethical but also harm the long-term interests of the recommender system itself. As a result, fairness issues in recommender systems have recently attracted increasing attention
The Metaverse as a Virtual Form of Smart Cities: Opportunities and Challenges for Environmental, Economic, and Social Sustainability in Urban Futures
Data infrastructures, economic processes, and governance models of digital platforms are increasingly pervading urban sectors and spheres of urban life. This phenomenon is known as platformization, which has in turn given rise to the phenomena of platform society, where platforms have permeated the core of urban societies. A recent manifestation of platformization is the Metaverse, a global platform project launched by Meta (formerly Facebook) as a globally operating platform company. The Metave
Artificial empathy in marketing interactions: Bridging the human-AI gap in affective and social customer experience
Abstract Artificial intelligence (AI) continues to transform firm-customer interactions. However, current AI marketing agents are often perceived as cold and uncaring and can be poor substitutes for human-based interactions. Addressing this issue, this article argues that artificial empathy needs to become an important design consideration in the next generation of AI marketing applications. Drawing from research in diverse disciplines, we develop a systematic framework for integrating artificia
Recent progress on vascular endothelial growth factor receptor inhibitors with dual targeting capabilities for tumor therapy
Vascular endothelial growth factor receptors (VEGFRs) are a family of receptor protein tyrosine kinases that play an important role in the regulation of tumor-induced angiogenesis. Currently, VEGFR inhibitors have been widely used in the treatment of various tumors. However, current VEGFR inhibitors are limited to a certain extent due to limited clinical efficacy and potential toxicity, which hinder their clinical application. Thus, the development of new strategies to improve the clinical outco
Challenges to implementing artificial intelligence in healthcare: a qualitative interview study with healthcare leaders in Sweden
BACKGROUND: Artificial intelligence (AI) for healthcare presents potential solutions to some of the challenges faced by health systems around the world. However, it is well established in implementation and innovation research that novel technologies are often resisted by healthcare leaders, which contributes to their slow and variable uptake. Although research on various stakeholders' perspectives on AI implementation has been undertaken, very few studies have investigated leaders' perspectives
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis
BACKGROUND: We aimed to evaluate the use of baricitinib, a Janus kinase (JAK) 1-2 inhibitor, for the treatment of patients admitted to hospital with COVID-19. METHODS: This randomised, controlled, open-label, platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple possible treatments in patients hospitalised with COVID-19 in the UK. Eligible and consenting patients were randomly allocated (1:1) to either usual standard of care alone (usual care group) or usua
Fairness perceptions of algorithmic decision-making: A systematic review of the empirical literature
Algorithmic decision-making increasingly shapes people's daily lives. Given that such autonomous systems can cause severe harm to individuals and social groups, fairness concerns have arisen. A human-centric approach demanded by scholars and policymakers requires considering people's fairness perceptions when designing and implementing algorithmic decision-making. We provide a comprehensive, systematic literature review synthesizing the existing empirical insights on perceptions of algorithmic f