Research (22)
Machine learning algorithms estimating prognosis and guiding therapy in adult congenital heart disease: data from a single tertiary centre including 10 019 patients
AIMS: To assess the utility of machine learning algorithms on estimating prognosis and guiding therapy in a large cohort of patients with adult congenital heart disease (ACHD) or pulmonary hypertension at a single, tertiary centre. METHODS AND RESULTS: We included 10 019 adult patients (age 36.3 ± 17.3 years) under follow-up at our institution between 2000 and 2018. Clinical and demographic data, ECG parameters, cardiopulmonary exercise testing, and selected laboratory markers where collected an
Exploring Consumer Behavior in Virtual Reality Tourism Using an Extended Stimulus-Organism-Response Model
Although virtual reality (VR) is an emerging technology in tourism, little research has been conducted on what factors make consumers visit destinations presented by VR. To address this gap in the literature, this study developed a theoretical framework including authentic experience, cognitive and affective responses, attachment, and visit intention with VR tourism using a stimulus-organism-response (SOR) theory. The results revealed significant impacts of authentic experience on cognitive and
Agriculture 4.0: Broadening Responsible Innovation in an Era of Smart Farming
Agriculture is undergoing a new technology revolution supported by policy-makers around the world. While smart technologies, such as Artificial Intelligence, robotics, and the Internet of Things, could play an important role in achieving enhanced productivity and greater eco-efficiency, critics have suggested that the consideration of social implications is being side-lined. Research illustrates that some agricultural practitioners are concerned about using certain smart technologies. Indeed, so
Artificial Intelligence and the Future of Primary Care: Exploratory Qualitative Study of UK General Practitioners’ Views
BACKGROUND: The potential for machine learning to disrupt the medical profession is the subject of ongoing debate within biomedical informatics and related fields. OBJECTIVE: This study aimed to explore general practitioners' (GPs') opinions about the potential impact of future technology on key tasks in primary care. METHODS: In June 2018, we conducted a Web-based survey of 720 UK GPs' opinions about the likelihood of future technology to fully replace GPs in performing 6 key primary care tasks
A Review on Application of Artificial Intelligence in Teaching and Learning in Educational Contexts
Innovative educational technologies have revolutionized the methods of teaching and learning. Recently, with advancements of artificial intelligence, higher education has begun to adopt new technologies. This conceptual review paper aims to investigate the emergence of using artificial intelligence in teaching and learning in education. It examines the educational consequences of emergent technologies on how institutions teach and the way students learn. This study intends to predict the role of
The Multidisciplinary Approach to Alzheimer's Disease and Dementia. A Narrative Review of Non-Pharmacological Treatment
Background. Alzheimer’s disease (AD) and dementia are chronic diseases with progressive deterioration of cognition, function and behavior leading to severe disability and death. The prevalence of AD and dementia is constantly increasing because of the progressive aging of the population. These conditions represent a considerable challenge to patients, their family and caregivers, and the health system, because of the considerable need for resources allocation. There is no disease modifying inter
Data mining for health: staking out the ethical territory of digital phenotyping
Digital phenotyping uses smartphone and wearable signals to measure cognition, mood, and behavior. This promising new approach has been developed as an objective, passive assessment tool for the diagnosis and treatment of mental illness. Digital phenotyping is currently used with informed consent in research studies but is expected to expand to broader uses in healthcare and direct-to-consumer applications. Digital phenotyping could involve the collection of massive amounts of individual data an
ZuCo, a simultaneous EEG and eye-tracking resource for natural sentence reading
We present the Zurich Cognitive Language Processing Corpus (ZuCo), a dataset combining electroencephalography (EEG) and eye-tracking recordings from subjects reading natural sentences. ZuCo includes high-density EEG and eye-tracking data of 12 healthy adult native English speakers, each reading natural English text for 4-6 hours. The recordings span two normal reading tasks and one task-specific reading task, resulting in a dataset that encompasses EEG and eye-tracking data of 21,629 words in 11
Artificial Intelligence and Big Data in Public Health
Artificial intelligence and automation are topics dominating global discussions on the future of professional employment, societal change, and economic performance. In this paper, we describe fundamental concepts underlying AI and Big Data and their significance to public health. We highlight issues involved and describe the potential impacts and challenges to medical professionals and diagnosticians. The possible benefits of advanced data analytics and machine learning are described in the cont
Deep convolutional networks do not classify based on global object shape
Deep convolutional networks (DCNNs) are achieving previously unseen performance in object classification, raising questions about whether DCNNs operate similarly to human vision. In biological vision, shape is arguably the most important cue for recognition. We tested the role of shape information in DCNNs trained to recognize objects. In Experiment 1, we presented a trained DCNN with object silhouettes that preserved overall shape but were filled with surface texture taken from other objects. S
Machine Learning and AI for Risk Management
We explore how machine learning and artificial intelligence (AI) solutions are transforming risk management. A non-technical overview is first given of the main machine learning and AI techniques of benefit to risk managementRisk management. Then a review is provided, using current practice and empirical evidence, of the application of these techniques to the risk management fields of credit risk, market risk, operational risk, and complianceCompliance (‘RegTech’). We conclude with some thoughts
Autonomous weapons systems, killer robots and human dignity
One of the several reasons given in calls for the prohibition of autonomous weapons systems (AWS) is that they are against human dignity (Asaro in Int Rev Red Cross 94(886):687–709, 2012; Docherty in Shaking the foundations: the human rights implications of killer robots, Human Rights Watch, New York, 2014; Heyns in S Afr J Hum Rights 33(1):46–71, 2017; Ulgen in Human dignity in an age of autonomous weapons: are we in danger of losing an ‘elementary consideration of humanity’? 2016). However the
Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges
Gut microbiota diversity across ethnicities in the United States
Composed of hundreds of microbial species, the composition of the human gut microbiota can vary with chronic diseases underlying health disparities that disproportionally affect ethnic minorities. However, the influence of ethnicity on the gut microbiota remains largely unexplored and lacks reproducible generalizations across studies. By distilling associations between ethnicity and differences in two US-based 16S gut microbiota data sets including 1,673 individuals, we report 12 microbial gener
The Paradigms of Industry 4.0 and Circular Economy as Enabling Drivers for the Competitiveness of Businesses and Territories: The Case of an Italian Ceramic Tiles Manufacturing Company
Sustainable development and the circular economy are two important issues for the future and the competitiveness of businesses. The programs for the integration of sustainability into industrial activities include the reconfiguration of production processes with a view to reducing their impact on the natural system, the development of new eco-sustainable products and the redesign of the business model. This paradigm shift requires the participation and commitment of different stakeholder groups
Data Statements for Natural Language Processing: Toward Mitigating System Bias and Enabling Better Science
In this paper, we propose data statements as a design solution and professional practice for natural language processing technologists, in both research and development. Through the adoption and widespread use of data statements, the field can begin to address critical scientific and ethical issues that result from the use of data from certain populations in the development of technology for other populations. We present a form that data statements can take and explore the implications of adopti
Big data hurdles in precision medicine and precision public health
BACKGROUND: Nowadays, trendy research in biomedical sciences juxtaposes the term 'precision' to medicine and public health with companion words like big data, data science, and deep learning. Technological advancements permit the collection and merging of large heterogeneous datasets from different sources, from genome sequences to social media posts or from electronic health records to wearables. Additionally, complex algorithms supported by high-performance computing allow one to transform the
Examining patterns of adversity in Chinese young adults using the Adverse Childhood Experiences—International Questionnaire (ACE-IQ)
Predicting adverse drug reactions through interpretable deep learning framework
BACKGROUND: Adverse drug reactions (ADRs) are unintended and harmful reactions caused by normal uses of drugs. Predicting and preventing ADRs in the early stage of the drug development pipeline can help to enhance drug safety and reduce financial costs. METHODS: In this paper, we developed machine learning models including a deep learning framework which can simultaneously predict ADRs and identify the molecular substructures associated with those ADRs without defining the substructures a-priori
Search and rescue with autonomous flying robots through behavior-based cooperative intelligence
A swarm of autonomous flying robots is implemented in simulation to cooperatively gather situational awareness data during the first few hours after a major natural disaster. In computer simulations, the swarm is successful in locating over 90% of survivors in less than an hour. The swarm is controlled by new sets of reactive behaviors which are presented and evaluated. The reactive behaviors integrate collision avoidance, battery recharge, formation control, altitude maintenance, and a variety
Trusting Intelligent Machines: Deepening Trust Within Socio-Technical Systems
Intelligent machines have reached capabilities that go beyond a level that a human being can fully comprehend without sufficiently detailed understanding of the underlying mechanisms. The choice of moves in the game Go (generated by Deep Mind?s Alpha Go Zero [1]) are an impressive example of an artificial intelligence system calculating results that even a human expert for the game can hardly retrace [2]. But this is, quite literally, a toy example. In reality, intelligent algorithms are encroac
PASNet: pathway-associated sparse deep neural network for prognosis prediction from high-throughput data
BACKGROUND: Predicting prognosis in patients from large-scale genomic data is a fundamentally challenging problem in genomic medicine. However, the prognosis still remains poor in many diseases. The poor prognosis may be caused by high complexity of biological systems, where multiple biological components and their hierarchical relationships are involved. Moreover, it is challenging to develop robust computational solutions with high-dimension, low-sample size data. RESULTS: In this study, we pr