{
  "id": 13621,
  "url": "https://arxiv.org/abs/2607.22143v1",
  "title": "TriGlue: a Biology-Inspired Generative Model for Generating Molecular Glue-Induced Ternary Complex",
  "summary": "Molecular glue degraders have emerged as a promising strategy for targeted protein degradation by inducing ternary complex formation between an E3 ubiquitin ligase and a target protein. Despite their therapeutic potential, computational design of molecular glues remains largely unexplored. Unlike conventional structure-based drug design, molecular glue design is governed by the unknown protein-protein interface and requires the simultaneous modeling of ligand generation, protein-protein docking,",
  "authors": "Yuliang Yan, Shuo Yan, Haochun Tang, Yiqin Sun, Enyan Dai",
  "category": "research",
  "topics": "healthcare,biotech",
  "orgs": null,
  "regions": null,
  "published_at": "2026-07-24T09:41:29.000Z",
  "fetched_at": "2026-07-27T05:10:06.638Z",
  "source_slug": "arxiv-ethics",
  "source_name": "arXiv",
  "source_homepage": "https://arxiv.org",
  "ethics_ai_record_url": "https://ethics.ai/record/13621",
  "original_url": "https://arxiv.org/abs/2607.22143v1",
  "evidence_status": "source-only",
  "attribution": "via ethics.ai"
}